Hígado graso, dieta mexicana, genética y microbioma: de la tradición a la enfermedad

Alan Fabricio Cano Méndez; José Rafael Fuentes Martínez; Paola Berenice Mass Sanchez

Authors

Alan Fabricio Cano Méndez Facultad de Ciencias Médicas y Biológicas "Dr. Ignacio Chávez", Universidad Michoacana de San Nicolás de Hidalgo. Morelia, Michoacán, México. https://orcid.org/0009-0009-8620-0962
José Rafael Fuentes Martínez Laboratorio de Microbiología, Hospital General de Zona No. 8, Instittuto Mexicano del Seguro Social. Ciudad de México, México.
Paola Berenice Mass Sanchez Centro de Bioquímica, Facultad de Medicina y Hospital Universitario de Colonia, Universidad de Colonia. Colonia, Alemania. Departamento de Pediatría y Medicina Adolescente, Facultad de Medicina y Hospital Universitario de Colonia, Universidad de Colonia. Colonia, Alemania. https://orcid.org/0000-0001-9185-7613

Keywords:

fatty liver, diet, microbiome

Abstract

Fatty liver, also known as hepatic steatosis, is a condition in which fat accumulates in liver cells, which can lead to inflammation, insulin resistance and more serious diseases such as cirrhosis or liver cancer. In Mexico, the increased prevalence of fatty liver is closely related to dietary habits, specially the high consumption of processed foods, saturated fats and added sugars. Genetics and intestinal microbiota also have a significant influence on liver health, so a better understanding of the mechanisms that intercommunicate in this disease is crucial to prevent and treat this condition.

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Author Biographies

José Rafael Fuentes Martínez, Laboratorio de Microbiología, Hospital General de Zona No. 8, Instittuto Mexicano del Seguro Social. Ciudad de México, México.

Academic degree: Master of Science in Infectious Diseases.
Postgraduate research area: Molecular analysis of multidrug resistant bacteria.
Current assignment: clinical laboratory technician in the clinical laboratory of the general hospital of zone 8 of IMSS CDMX.

Paola Berenice Mass Sanchez, Centro de Bioquímica, Facultad de Medicina y Hospital Universitario de Colonia, Universidad de Colonia. Colonia, Alemania. Departamento de Pediatría y Medicina Adolescente, Facultad de Medicina y Hospital Universitario de Colonia, Universidad de Colonia. Colonia, Alemania.

Dr. Paola Berenice Mass-Sanchez is a researcher specializing in liver diseases and fibrosis. She obtained her BSc and MSc degrees from the National Autonomous University of Mexico in 2017 and 2019, respectively, before moving to Germany to pursue her PhD at the RWTH Aachen University Hospital. Her doctoral research focused on preclinical models of hepatocellular carcinoma (HCC) in non-alcoholic fatty liver disease (NAFLD), examining key molecular and cellular mechanisms. After her PhD, Dr. Mass-Sanchez joined Dr. Gerhard Sengle's group at the University of Cologne as a research assistant. Her current work explores the role of extracellular matrix proteins in fibrosis, improving the understanding of their implications in the progression of various diseases.

References

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